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- ArticleWebster DJ, Gough DC, Craven JL.Br J Surg. 1978 Apr;65(4):291-2.Fifty-three patients with symptomatic haemorrhoids have been studied in a double-blind cross-over trial of a bulk forming agent (ispaghula husk) against a placebo. Although only 11 per cent of patients ocmplained of constipation, a significant benefit in symptoms and improved bowel habit was demonstrated.